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| O.T. | 1928 | William Pence | Martha Elizabeth Davidson | Robeson Co., NC | Unknown | None |
| Oakey (m) | 1860 | Wilson | Mercy A. Cox | Marion County, SC | Unknown | None |
| Oakley Gordon | 1922 | Nathan Clifford | Melissa Frances Howerin | Carteret County, NC | Audrey Irene Potter | None |
| Oates Stephens | 1815 | James R. | Artesia Oates Stevens | Sampson Co., NC | Mary Ann Byrd | None |
| Obediance | 1758 | Jacob A. | Penelope Lobar | New Hanover Co., NC | Unknown | None |
| Oceania | 1861 | James Bryant | Letitia McCool | Wayne Co., GA | James Poppell | None |
| Ocie Lama | 1898 | Patrick Evander | Lorenda Tyler | Marion County, SC | Daniel Shaw Hayes | None |
| Oda J. | 1879 | Daniel F. (David) | Dolly A. Shelley | Horry Co., SC | Unknown | None |
| Odell | 1886 | Dempsey | Eliza Jane Stackhouse | Marion County, SC | Loula Derham | None |
| Odis | 1924 | Julius P. | Avie Benton | Horry County, SC | Gertrude Shackelford | None |
| Olen | 1922 | Pearly Emmanuel | Maggie Edna Owens | Horry County, SC | Gladys Jones | None |
| Olen McClain | 1913 | John McClain | Leonora Myrtice Smith | Van Zandt Co., TX | Mary E. Akins | Dorothy Simmons, Helen ? |
| Oleta Ellen | 1930 | Phillip Jefferson | Attie Jane Wilson | FL | L.T. Newmons | Unknown |
| Oletha | 1905 | Jesse Braxter | Delia Elma Wilson | FL | William Winfred Sirmons | Unknown |
| Olin | 1884 | Alexander Lorenzo | Sarah Ann Gaskin | Horry County, SC | Viola Turner | None |
| Olin Carlisle | 1909 | Olin | Viola Turner | Horry County, SC | Edna Maude Waters | None |
| Olin Paul | 1956 | Jack Lester | Ruth Carol Vaught | Columbus Co., NC | Dabney Susan Pewitt | None |
| Olive | 1850 | William S. | Matilda Sterling | Horry County, SC | Daniel Pinkney Blackwell | None |
| Olive Retia | 1911 | Clemon Thomas | Elizabeth Jane Williams | FL | Never | None |
| Oliver Augustine | 1877 | George Washington | Mary Anna Sellers | Brunswick Co., NC | Mamie Arnold Swain | None |
| Oliver Edison | 1916 | Oliver Augustine | Mary Arnold Swain | Brunswick Co., NC | None | None |
| Oliver H. | 1848 | Thomas A. | Mary Anne Humphrey | Robeson Co., NC | Sarah L. "Tennessee" Lindsey | None |
| Oliver Verlon | 1933 | Jessie Bennie | Veleter Brackins | Holmes Co., FL | Myrtie Juanita Martin | None |
| Olivia | 1883 | Jacob A. | Penn Penelope Johnson | Brunswick Co., NC | Unknown | None |
| Olivia "Obie" | 1890 | Boaz, Jr. | Floy Jane Parker | Sampson Co., NC | Levi P. Surles | None |
| Olivia Roberta | 1881 | William Montgomery | Mariam L. Marshburn | Bladen County, NC | John D. Thomas | None |
| Ollie | 1901 | Oliver Augustine | Mary Arnold Swain | Brunswick Co., NC | F. Danford | None |
| Ollie Herndon | 1895 | Lula | Wilbur Fulford Lewis | Carteret Co., NC | Unknown | None |
| Ollie Laverne | 1922 | Jet Ollen | Addie Eliza Bostick | Motley, TX | None | None |
| Ollie Mae | 1905 | John McClain | Leonora Myrtice Smith | Rankin Co., MS | Troy Clinton Gray | None |
| Ollie Mae | 1909 | Albert | Mamie Fussell | Geneva Co., AL | Larou Mixson | None |
| Oma Benjamin | 1894 | Pinkney | Mary P. ? | Horry Co., SC | Alberta Skipper | None |
| Ona Belle | 1911 | Jesse Braxter | Delia Elma Wilson | FL | J.L. Gill | Unknown |
| Opal | 1919 | Alexander "Zander" | Mamie Walker | Columbus Co., NC | Corbett Watts | None |
| Opal Marie | 1957 | Grady Washington | Allie Mae Hamrick | Leon Co., FL | Archie Wade Strickland | None |
| Ora Belle | 1909 | Joseph Jackson | Mary Ann "Texas" Hagin | Port Arthur, TX | Unknown | None |
| Ora Christine | 1928 | Emery Steven | Bessie Pearl Free | Louisiana | Unknown | None |
| Ora Leah | 1930 | Lury Matthew | Mamie Lay Soles | Columbus Co., NC | None | None |
| Ora Maye | 1921 | Joe | Hannah Bowling | Leslie Co., KY | Grover Cleveland Brown | None |
| Orelia Delphine | 1863 | Jordan | Margaret Malone | Mobile, AL | Joe Burrage | None |
| Oren Elvis | 1915 | Clemon Thomas | Elizabeth Jane Williams | Taylor Co., FL | Caroline Odell Frier | None |
| Orena | 1842 | John B. | Elenor ? | Robeson Co., NC | Unknown | None |
| Orena | 1916 | Foster Price | Rena Cooper | Horry Co., SC | Ernest Roberts | Mr. Thrasher |
| Orilla Keithan (m) | 1862 | Alexander | Katie Edwards | Marion County, SC | Ms. Finkley | None |
| Oscar | 1919 | Julius P. | Avie Benton | Horry County, SC | Leona Inman | None |
| Oscar | 1920 | Cecil W. | Lena ? | Charleston, SC | Unknown | None |
| Oscar Byrd | 1898 | George Washington, Jr. | Hannah Jane Hewett | Brunswick Co., NC | Sallie Edwards | None |
| Oscar Green | 1869 | William Green | Louisa Mae Collins | Thomas Co., GA | Mary Virginia Tinsley | None |
| Oscar Green | 1883 | Franklin Pearce | Sarah A. Dickinson | Carteret Co., NC | Sadie Meade | Lossie Davis |
| Oscar Herley | 1895 | Edwin Neuil | Lilla Estelle Hamm | Jackson County, FL | Unknown | None |
| Oscar L. | 1879 | John Thomas | Mary Frances Coleman | Burleson Co., TX | Mattie Viola Welch | None |
| Oscar Paul | 1910 | John Shelby | Annie G. Charles | New Hanover Co., NC | Edna Langston | None |
| Oscar Perry "Osco" | 1855 | Dr. Daniel | Sarah Ann Jones | Union Co., AR | Unknown | None |
| Oscar Talmadge | 1924 | Walker Talmadge | Hattie V. George | Brunswick Co., NC | Gene Harwell | None |
| Oscar Thomas | 1901 | Robert Ford | Hortense Davis | Brunswick Co., NC | Clara Myrtle Eichhorn | None |
| Oscar Thomas, Jr. | 1923 | Oscar Thomas | Clara Myrtle Eichhorn | Brunswick Co., NC | Florence Rowena Swain | None |
| Oswald "Ossie" | 1880 | James Henry | Susan Daniels | Arkansas | Susie F. Rushing | None |
| Oswald Knox | 1858 | Henry Dewey | Nancy Stephens | Arkansas | Annie Bell Cobb | None |
| Otho McClain | 1916 | Willie Leath | Emily Levcy Holmes | Van Zandt Co., TX | Unknown | None |
| Otis "Bo" | 1925 | Oswald "Ossie" | Unknown | Arkansas | Unknown | None |
| Ottie Bright | 1887 | Patrick Evander | Lorenda Tyler | Marion County, SC | Hosea M. Elliott | None |
| Ottis W. | 1922 | Norris W. | Maudie Dans | Louisiana | Unknown | None |
| Ouida Talma | 1910 | Albert | Mamie Fussell | Geneva Co., AL | Hansel Turner | Lester McKnight |
| Owen | 1900 | John William | Annie Williams | Carteret Co., NC | Never | None |
| Owen Robinson | 1900 | Doc Rolen | Pennie Ann Starling | Sampson Co., NC | Never | Never |